Safety, Pharmacokinetics, and Efficacy of 100, 150, and 200 mg Risedronate Administered to Women With Low BMD

Inclusion Criteria: * be postmenopausal 5 years based on medical history; follicle stimulating hormone and estradiol will be evaluated for any patient less than 65 years of age, who has undergone hysterectomy without bilateral oophorectomy, to ensure the patient is postmenopausal Exclusion Criteria: * use of any of the following medications within 3 months of starting study drug or use of any of the following medications for more than 1 month at any time within 6 months prior to starting study drug: * oral or parenteral glucocorticoids (5 mg prednisone or equivalent per day) * anabolic steroids * estrogen, raloxifene or estrogen-related drugs, eg, tamoxifen, tibolone, (except for low dose vaginal creams, tablets or insertable estrogen ring * progestogen * calcitonin * vitamin D supplements (greater than 800 IU per day) * calcitriol, calcidiol, or alfacalcidol * any bisphosphonate * fluoride (10 mg per day) * strontium and other bone active agents * parathyroid hormone * heparin, warfarin, and other similar anticoagulants