The study aims to examine whether the combination of Lopinavir/Ritonavir plus Ribavirin for treatment of severe acute respiratory syndrome (SARS) is superior to placebo.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
340
Department of Health
Hong Kong, China
Kowloon Hospital
Hong Kong, China
Prince of Wales Hospital
Hong Kong, China
Princess Margaret Hospital
Hong Kong, China
Development of severe SARS
Time frame: Any time during the acute illness
Adverse events
Time frame: Throughout the illness period
SARS-CoV Viral load
Time frame: Throughout the illness period
Immunological profile
Time frame: Throughout the illness period
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Queen Mary Hospital
Hong Kong, China
The Chinese University of Hong Kong
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The University of Hong Kong
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Tuen Mun Hospital
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United Christian Hospital
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