Water and the Gastropressor Response - Diurnal Variability

N/AActive Not RecruitingNCT00581373

Satish R. Raj20 enrolled

Overview

We will test the null hypothesis that there is no diurnal (morning to afternoon)variability in the blood pressure response to the ingestion of water 16 oz.

We will test the null hypothesis that there is no diurnal (morning to afternoon)variability in the blood pressure response to the ingestion of water 16 oz. This will involve having participants ingest 16 oz water rapidly in the morning and in the afternoon.

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Orthostatic Hypotension

Interventions

water 16 fl ozOTHER

water 16 fl oz in AM and repeat in late afternoon

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * orthostatic intolerance Exclusion Criteria: * pregnancy

Locations (1)

Vanderbilt University

Nashville, Tennessee, United States

Outcomes

Primary Outcomes

blood pressure

peak systolic blood pressure within 60 min of ingestion

Time frame: 1 day

Secondary Outcomes

heart rate

heart rate at peak BP within 60 min of ingestion

Time frame: 1 day

Data from ClinicalTrials.gov

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