Radiation Biodosimetry in Patients Treated With Total Body Irradiation (TBI)

Inclusion Criteria: * Patients greater than 4 years of age at Memorial Sloan-Kettering Cancer Center * Must be undergoing hematopoietic stem cell transplantation (either autologous or allogenic) in conjunction with a conditioning regimen that includes TBI (single or multiple fraction) * Functional central venous catheter Exclusion Criteria: * No subjects will be excluded from the proposed research study for demographic reasons. Treatment with growth factors, such as keratinocyte growth factor (KGF), will not be grounds for exclusion. * Subjects who will receive radiation therapy within 5 days prior to TBI will be excluded. * Subjects who will receive systemic antineoplastic chemotherapy within 7 days prior to TBI not have research bloods collected. Only urine will be collected from these patients. * Based on current knowledge, we will not a priori exclude patients based on disease status (ie, patients in or out of remission will be included in this study), type of disease(ie, chromosomal breakage syndromes), or previous therapies (unless exclusion criteria is met).