Closure Of Patent Ductus Arteriosus With the AMPLATZER Duct Occluder the AMPLATZER® Duct Occluder

Inclusion Criteria: * Patients with a demonstrated patent ductus arteriosus * Body weight \> 5 Kilograms Exclusion Criteria: * Pulmonary vascular resistance above 8 Woods units or a Rp/Rs \>0.4. * Additional cardiac or non-cardiac abnormality that can reasonably be expected to significantly affect the patient's health adversely in the next two years, i.e.: cancer, Eisenmenger's syndrome, other serious congenital heart disease. * Pelvic vein or inferior vena cava thrombosis * Sepsis (local/generalized) or any type of infection that cannot be successfully treated prior to device placement. * History of repeated pulmonary infection * Demonstrated intracardiac thrombi on echocardiography • Inability to obtain informed consent