Effect of Coffee on Gastro-Esophageal Disease in Patients With Symptoms of Reflux

University of California, Davis7 enrolled

Overview

Investigation evaluating the effect of coffee on gastro-esophageal reflux disease.

Many patients with gastro-esophageal reflux disease (GERD) report that drinking coffee causes heartburn. The purpose of this study is to investigate the effects of coffee on gastro-esophageal acid reflux, and its relation to esophageal motility parameters in patients who are already scheduled to undergo 48 hour wireless pH testing as a result of having symptoms suggestive of GERD. The specific aims are to evaluate the effects of coffee on GERD during daily life and to elucidate the underlying pathogenic mechanism by which coffee induces reflux.

Study Type

INTERVENTIONAL

Allocation

Purpose

SUPPORTIVE_CARE

Masking

NONE

Enrollment

Conditions

GERD

Interventions

CoffeeOTHER

3 cups of coffee over a 24 hour period

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * persons undergoing wireless pH testing for diagnosis and treatment of GERD Exclusion Criteria: * those under the age of 18 * pregnant and lactating women * those who do not meet the inclusion criteria

Locations (1)

University of California Davis Medical Center

Sacramento, California, United States

Outcomes

Primary Outcomes

coffee leads to reflux events

Time frame: 48 hours

Data from ClinicalTrials.gov

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