A Double Blind, Placebo Controlled Trial of Quetiapine in Anorexia Nervosa, a Dual Site Study

Phase 2TerminatedNCT00584688

University of South Florida24 enrolled

Overview

Research studies raise the possibility that medications such as quetiapine may improve mood or reduce obsessions in people with anorexia nervosa and may even help to normalize appetite. The medication quetiapine also known as seroquel works by activating certain systems in the brain, such as ones known as dopamine and serotonin chemical systems in the brain.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Enrollment

Conditions

Anorexia Nervosa

Interventions

quetiapineDRUG

quetiapine dosage will be titrated to subject tolerance beginning at 50 mg every 24 hours upwards to 400 mg every 24 hours.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Must be aged 18-65 * Must be at least 15% below ideal body weight Exclusion Criteria: * Allergy to quetiapine * Diagnosis of schizophrenia

Locations (1)

University of South Floirda

Tampa, Florida, United States

Outcomes

Primary Outcomes

To determine efficacy of seroquel in anorexia nervosa

Time frame: 8 weeks

Data from ClinicalTrials.gov

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