Vascular Effects of Sertraline in Heart Failure

Yale University4 enrolled

Overview

To determine the effects of chronic sertraline treatment on brachial artery flow-mediated dilation in patients with chronic heart failure and depression

Study Type

OBSERVATIONAL

Enrollment

Conditions

Heart Failure Depression

Interventions

sertralineDRUG

open label 25-50 mg daily as tolerated

Eligibility

Sex: ALLMin age: 21 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Chronic heart failure with LVEF\<40%, age \>21 years * Depression requiring medical treatment with sertraline Exclusion Criteria: * Known intolerance of sertraline

Locations (1)

Yale University School of Medicine

New Haven, Connecticut, United States

Outcomes

Primary Outcomes

Brachial artery flow-mediated dilation

Time frame: 2 months

Data from ClinicalTrials.gov

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