Inflammation as a Predictor in Cardioversion of Atrial Fibrillation

Creighton University45 enrolled

Overview

The laboratory test, C-Reactive Protein (CRP), has become well established as a marker of inflammation. Recently a high CRP level (indicating an increase in inflammation) was identified as a risk factor for atrial fibrillation. We are conducting this study with patients such as yourself with atrial fibrillation who are planning to undergo cardioversion to determine what sort of relationship exists between CRP levels and atrial fibrillation. We will then look at success rates of converting atrial fibrillation to normal sinus rhythm, compared to patients' CRP levels.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Atrial Fibrillation

Interventions

CardioversionPROCEDURE

Baseline hsCRP will be drawn the morning of, prior to, cardioversion. An EKG to document the patient's rhythm will be obtained at the one-month mark

Eligibility

Sex: ALLMin age: 19 Years

Medical Language ↔ Plain English

Inclusion Criteria * Atrial fibrillation patients referred for DC cardioversion * On stable medical therapy Exclusion Criteria * Known chronic inflammatory states such as infections, rheumatoid arthritis or known vasculitides. * Patients having undergone recent surgery or who are on steroid therapy for any reason will be excluded.

Locations (1)

Creighton University Medical Center

Omaha, Nebraska, United States

Outcomes

Primary Outcomes

We hypothesize that a higher hsCRP is associated with higher failure rates in patients undergoing cardioversion for atrial fibrillation

Time frame: 1 month

Secondary Outcomes

secondary endpoint will be if a new inflammatory disease state is diagnosed at the one-month mark.

Time frame: 1 month

Data from ClinicalTrials.gov

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