2PX (Topical Strontium Chloride Hexahydrate) in Patients With Post-Amputation Stump Pain.

Inclusion Criteria: * Lower limb amputation at least 6 months prior to inclusion * Presenting with moderate-to-severe pain intensity (above 50 on 100 mm VAS) at screening, to be confirmed prior to randomisation as: Mean (over the 14 days run-in period) stump API rating above 50 on a 100 mm VAS * Outpatients, aged 18 years and above * Written informed consent Exclusion Criteria: * Subjects who have received treatment with any potent opioid in the 4 weeks prior to study entry (i.e. an opioid assumed to cause abstinence symptoms upon abrupt cessation) * Subjects taking any analgesic medication (except for rescue medication as defined in this protocol) * Subjects with expressed dissatisfaction with their prosthesis comfort * Pregnant or breast-feeding women * Any malignant disease * Subjects who have received an investigational drug or used an investigational device in the 30 days prior to study entry. * Subjects unable to comply with the study assessments * Subjects with documented or suspected alcohol or drug abuse