Evaluation of Potential Vitamin D Effects on Muscle: a Pilot Study

University of Wisconsin, Madison50 enrolled

Overview

People who do not have adequate amounts of vitamin D develop weakness of leg and arm muscles. This study will determine if vitamin D supplementation benefits muscle functions important for swallowing, bladder and bowel function.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Dysphagia Fecal Incontinence Urinary Incontinence

Interventions

Ergocalciferol (vitamin D2)OTHER

50,000 IU 3 times weekly for 4 weeks

Eligibility

Sex: ALLMin age: 70 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Patients who present for evaluation to the UW Geriatric clinic including Dr. Pryzbelski's subspecialty, or Osteoporosis clinics * Age 70 years or older * Cognitively intact, as determined by the attending physicians at above mentioned clinics Exclusion Criteria: * History of, on ongoing, renal failure * History of liver failure * Known malabsorption * Known disorders of parathyroid function, hyper/hypocalcemia, or other abnormalities of calcium or phosphate metabolism * Known history of vitamin D intoxication or granulomatous disease * active seizure disorder * Pain associated with temporomandibular joint (TMJ)

Locations (1)

UW Osteoporosis Clinical Research Program

Madison, Wisconsin, United States

Outcomes

Primary Outcomes

change in lingual strength and perceived swallow function

Time frame: 4 weeks

Secondary Outcomes

change in perceived bowel and bladder function

Time frame: 4 weeks

Data from ClinicalTrials.gov

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