Study to Evaluate Safety and Effectiveness of Spinal Sealant

Inclusion Criteria: * Patients who are scheduled for an elective spinal procedure that requires a dural incision will be considered for study participation. * Patient requires a procedure that involving surgical wound classification Class 1/Clean (per CDC criteria) * Presence of a non-watertight dural closure, either spontaneously or upon Valsala maneuver at 20-25 cm H20 for 5-10 seconds. Exclusion Criteria: * Active spinal and/or systemic infection * Patient requires additional spinal surgery within the study time period * Patient has had a previous spinal surgery involving dural exposure and/or entry at the same level(s) as the study procedure * Patient has a pre-existing external lumbar CSF drain or internal CSF shunt * Patient is participating in a clinical trial of another investigational device or drug * Patient with creatinine \> 2.0 mg/dL * Patient with total bilirubin \> 2.5 mg/dL * Pregnant or breast-feeding females or females who wish to become pregnant during the length of study participation * Patient has been treated with chronic steroid therapy (\>4 weeks) unless discontinued more than 6 weeks prior to surgery * Patient has documented history or significant coagulopathy with a PTT \>35 sec, PT/INR \>1.2, receiving asprin, or NSAIDS at the time of surgery * Patient receiving warfarin or heparin at the time of surgery * Patient has a diagnosed and documented compromised immune system and/or autoimmune disease * Patient has has chemotherapy treatment within 6 months prior to, or planned during the study * Patient has had prior radiation treatment to the surgical site or has planned radiation therapy within 30 days post procedure * Patient has known malignancy or other condition with prognosis shorter than 6 months * Patients with documented history of uncontrolled diabetes * Patient requires use of synthetic or non-autologous duraplasty material * Patient has a gap greater than 2mm remaining after primary dural closure * Patient has undergone laminoplasty decompression * Patient has undergone a syringomyelia procedure where the shunt is not placed in the subarachnoid position * Patient has undergone a Chiari Malformation procedure that does not entail a dural incision at or below the C1 level * The investigator determines that participation in the study may jeopardize the safety or welfare of the patient * The investigator determines that the patient should not be included in the study for reason(s) not already specified