The purpose of this study is to compare the effectiveness of over-the-counter remedies for dry mouth.
Xerostomia (dry mouth) is the most common late complication of radiation therapy for head and neck cancers. When patients are cured or survive for several years, xerostomia often becomes quite bothersome; it affects their quality of life. This study compares the effectiveness of seven over-the-counter remedies, 2 rinses, 3 sprays and 2 chewing gums. A computer program will make random assignments so that the patient nor the physician will choose the order in which the products are tried. The remedies will be used for one week each and at the end of each period the patient will fill out a questionaire.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
28
Chew gum 4 times a day with additional allowances for as needed. Fill out daily questionaire and an end of week.
Chew gum 4 times a day with additional allowances for as needed. Fill out daily questionaire and an end of week.
Rinse mouth 4 times a day with additional allowances for as needed. Fill out daily questionaire and an end of week questionaire
University of Oklahoma Health Sciences Center
Oklahoma City, Oklahoma, United States
The effectiveness of seven over-the-counter remedies for dry mouth as determined by amount of saliva output and a brief questionaire.
Time frame: 8-10 weeks
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Rinse mouth 4 times a day with additional allowances for as needed. Fill out daily questionaire and an end of week.
Spray mouth with mouth spray 4 times a day with additional allowances for as needed. Fill out daily questionaire and an end of week
Spray mouth 4 times a day with additional allowances for as needed. Fill out daily questionaire and an end of week