Efficacy and Safety of Cefditoren Pivoxil Versus Ciprofloxacin in Acute Uncomplicated Cystitis

Inclusion Criteria: * Non-pregnant adult females (\>= 18) * Clinical signs and symptoms of uncomplicated acute cystitis (dysuria, urgency, frequency, suprapubic pain) with symptoms starting \<=72 hours prior the study entry * Positive pre-treatment clean-catch midstream urine culture (\>= 103 CFU/ml) and pyuria (10 leukocytes/mm3 or more than 5 leukocytes/field 40x magnification) within the 48 hours prior to inclusion in the study * In vitro susceptibility testing of the isolated uropathogen to the drugs under study * Written informed consent Exclusion Criteria: * Males * Woman who are pregnant, nursing or not using a medically accepted, effective method of birth control * Three or more episodes of uncomplicated acute infections of the urinary tract during the past 12 months * Symptoms starting \>4 days prior to admission * Body temperature \>= 38.3ºC, back pain, chills or other manifestations suggestive of upper urinary infection * Evidence of structural or functional alterations of the urinary tract, such as calculi, stenosis, primary renal disease (eg. polycystic renal disease) or neurogenic bladder * Underlying disease predisposing to complicated urinary tract infections such as diabetes mellitus, immunosuppression, leucopenia, heart insufficiency, liver impairment and neoplastic processes