FCM Analysis GR in Steroid-Treatment Patients

Changhai Hospital150 enrolled

Overview

Monitoring the GR with a GR-MoAb and FITC-Dex probes by FCM would be useful and convenient in determination GR before the steroid treatment in clinical, especially in steroid resistant states, in order to design more efficient clinical treatment protocols.

In order to assess the efficacy of this method, 100 patients with nephrotic syndrome and systemic lupus erythematosus receiving sufficient prednisolone thereafter and 50 age- and sex-matched normal controls will be studied.

Study Type

OBSERVATIONAL

Enrollment

150

Conditions

Healthy

Eligibility

Sex: ALLMin age: 15 YearsMax age: 65 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Clinical diagnosis of SLE and NS Exclusion Criteria: * Receiving hormone replacement therapy or had received hormone replacement therapy in three months before start of the study * Received drugs or drinks containing alcohol within one month * Having symptom such as infection * Supersensitivity and endocrine disturbance.

Data from ClinicalTrials.gov

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