Acclimatization Mechanisms During Ascent to 7500m

University of Zurich37 enrolled

Overview

The trial evaluates the role of ascent protocol on acute mountain sickness and cardio-respiratory physiology during an ascent to Muztagh Ata (7546m). Two groups of mountaineers ascend with different acclimatization time to the summit. The prevalence and severity of symptoms of acute mountain sickness are evaluated along with physiologic variables.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Enrollment

Conditions

Acute Mountain Sickness

Interventions

ascent protocolBEHAVIORAL

ascent protocol for the two groups has different acclimatization time

Eligibility

Sex: ALLMin age: 18 YearsMax age: 70 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Healthy, physically fit subject * Mountaineering experience Exclusion Criteria: * Any type of cardiac or respiratory disease * Regular intake of any medication * History of high altitude pulmonary oedema * Severe acute mountain sickness at altitudes below 3500m or high altitude cerebral oedema.

Outcomes

Primary Outcomes

acute mountain sickness

Time frame: during ascent

Secondary Outcomes

mountaineering success, oxygen saturation, breathing pattern

Time frame: during ascent

Data from ClinicalTrials.gov

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