Effect of Nutrition on Muscle Protein Synthesis

Maastricht University Medical Center12 enrolled

Overview

The present proposal is designed to examine the effect of carbohydrate and protein co-ingestion on muscle protein synthesis during endurance type exercise activities. We hypothesize that muscle protein synthesis is higher when protein is co-ingested during exercise.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

DOUBLE

Enrollment

Conditions

Healthy

Interventions

carbohydrate and proteinDIETARY_SUPPLEMENT

The intake of carbohydrate and protein during endurance type exercise

Eligibility

Sex: MALEMin age: 18 YearsMax age: 28 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * recreationally endurance trained Exclusion Criteria: * BMI \> 25 kg/m2 * Not physically active

Outcomes

Primary Outcomes

Differences in muscle protein synthesis rates between carbohydrate and carbohydrate + protein.

Time frame: 1 day

Secondary Outcomes

Difference in whole-body protein synthesis and breakdown between carbohydrate and carbohydrate plus protein.

Time frame: 1 day

Data from ClinicalTrials.gov

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