A randomized, controlled pilot study examining how cellular energetics related to various wound treatment therapies in patients with diabetic foot ulcers.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Enrollment
50
continuous foam based negative pressure wound therapy
continuous gauze based negative pressure wound therapy
moist wound therapy
The Ohio State University Medical Center
Columbus, Ohio, United States
University of Texas Health Science Center San Antonio
San Antonio, Texas, United States
Compare Energy Charge Between Wound Treatment Therapies
Energy charge is a calculated ratio of the parameters ATP (µg), ADP (µg), and AMP (µg) which are measured with the same unit. Energy Charge is calculated as follows: Energy Charge = (ATP + (0.5 \* ADP)) / (ATP + ADP + AMP) Where, ATP = Adenosine triphosphate, ADP = Adenosine diphosphate, AMP = Adenosine monophosphate
Time frame: Day 0, Day 2, Day 7
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