Breast MRI is a fairly new technology, but it has been well studied. It is now used routinely in many patients with breast cancer. It has been shown to be useful in detecting areas of cancer that cannot be seen using other types of scans or tests. The purpose of this study is to see how often MRI can find other areas of cancer in women with one area of breast cancer, and to determine how having the MRI test affects their treatment. The purpose is also to study any areas of abnormality seen on your MRI with special methods that allow the images of your breast tissue and the microscopic analysis of your breast tissue to be compared very carefully. The study also aims to follow women who enter the study over a 10-year period to determine how often the breast cancer comes back.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
DIAGNOSTIC
Masking
NONE
Enrollment
115
The patient will then undergo a breast MRI as part of their preoperative work-up of DCIS. Biopsy of any suspicious areas by needle biopsy or at the time of surgery. If appropriate, repeat MRI after biopsy or surgery. Follow-up for 10 years (you will be contacted once a year to see how you are doing).
Memorial Sloan Kettering Cancer Center
Basking Ridge, New Jersey, United States
Memorial Sloan Kettering Cancer Center
Commack, New York, United States
Memorial Sloan Kettering Cancer Center
New York, New York, United States
To prospectively evaluate the value of preoperative breast MRI in women with core biopsy-proven DCIS.
Time frame: conclusion of the study
To determine the proportion of all patients in this study in whom breast MRI identifies at least one site of cancer separate from the index lesion.
Time frame: conclusion of the study
To estimate re-excision rates and mastectomy rates in patients with DCIS undergoing preoperative MRI.
Time frame: conclusion of the study
To estimate the proportion of patients with DCIS in which preoperative MRI will change surgical planning.
Time frame: conclusion of the study
To estimate the long-term ipsilateral breast recurrence rate in women with DCIS undergoing preoperative breast MRI.
Time frame: conclusion of the study
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