Structural Imaging and Cognitive Functions in Adult Stem Cell Transplant Recipients Treated With Chemotherapy Alone or in Combination With Radiotherapy

Inclusion Criteria: * Diagnosed with acute myeloid leukemia (AML), acute lymphoblastic leukemia (ALL), acute undifferentiated or biphenotypic leukemia, myelodysplastic syndrome (MDS), Hodgkin's lymphoma, (HL) or non-Hodgkin's lymphoma (NHL), and in complete remission at the time of enrollment * Are scheduled to undergo conditioning treatment with (1) total body radiation (TBI) and chemotherapy or (2) chemotherapy alone prior to receiving a myeloablative allogeneic HSCT * Between 18 and 70 years of age. * Are English speaking. * Have capacity to give consent. Healthy Control Inclusion Criteria: * Have no diagnosis of cancer except basal cell carcinoma * Between 18 and 70 years of age. * Are English speaking. * Have capacity to give consent Exclusion Criteria: * Patients with signs and/or symptoms of central nervous system disease as determined by their physician or by a brain MRI, either at the time of enrollment or during the study period. * With disease progression at the time of enrollment or during the study period * With self-reported Axis I psychiatric disorder (DSM-IV), major affective disorder (untreated), bipolar disorder, schizophrenia * With a history of a neurological disorder, neurodegenerative disease, or traumatic brain injury with loss of consciousness * With standard contraindications to MRI examinations Healthy Control Exclusion Criteria: * Exposure to chemotherapy or radiation therapy for any medical condition * With self-reported Axis I psychiatric disorder (DSM-IV), major affective disorder (untreated), bipolar disorder, schizophrenia * With a history of neurological disorders, neurodegenerative disease, or traumatic brain injury with loss of consciousness * With standard contraindications to MRI examinations