Day 3 Embryo Cryopreservation: Metabolic and Viability Analysis

V.K.V. American Hospital, Istanbul186 enrolled

Overview

Embryo preservation through freezing plays a significant role in human assisted reproduction. It provides an opportunity for patients to have more than one attempt following an ovarian stimulation cycle, thereby decreasing the exposure of patients to exogenous gonadotrophins and improving cumulative pregnancy rates. The purpose of this study is to compare effectiveness of two different freezing methods.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

186

Conditions

Fertilization in Vitro Preservation of Supernumerary Embryos

Interventions

VitrificationPROCEDURE

Embryos were vitrified according to a previously described technique

Slow freezingPROCEDURE

Embryos were frozen with slow freezing technique

Eligibility

Sex: FEMALEMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * ICSI with own gametes * Couples who did not wish to cryopreserve their excess embryos for possible transfer in a future cyle * Donating excess embryos for research purposes Exclusion Criteria: * Embryos derived from surgically retrieved spermatozoa * Blastocysts * Embryos of low quality (Grade 3 or 4 according to Hardarson)

Locations (1)

American Hospital of Istanbul

Istanbul, Turkey (Türkiye)

Outcomes

Primary Outcomes

Blastocyst development rate

Time frame: 3 days after thawing

Data from ClinicalTrials.gov

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