Treatment With Copper in Patients With Mild Alzheimer´s Dementia

Inclusion Criteria: * male or female patients * between 50 and 80 years * criteria of mild dementia * probable Alzheimer´s dementia according to NINCDS-ADRDA criteria * given written informed consent * having a relative who can fill out questionnaire; caregiver consent * free of serious and unstable somatic illness Exclusion Criteria: * unable to give informed consent * unable to take cholinesterase inhibitors * unapproved medication * moderate to severe Alzheimer´s disease * dementia of other etiology * history of alcohol, drug or medication abuse * other psychiatric disorder, e. g. schizophrenia * known copper and zinc storage disease * known copper and zinc intolerance * vegans * known severe allergies or intolerances * insufficient knowledge of the German language * female patients of childbearing potential, pregnant or nursing patients * participation in a clinical trial within the past 30 days before onset of this study * severe somatic diseases and high mortality rate AST, ALT, GGT, GLDH, AP or bilirubin being a two-fold above the normal range