Magnetic Resonance Imaging and Spectroscopy at High Field

Inclusion Criteria: * Healthy normal volunteers for imaging protocol optimization. Exclusion Criteria: * Patients with implanted surgical clips (hemostatic clips) or other ferromagnetic material, * Patients engaged in occupations or activities which may cause accidental lodging of ferromagnetic materials, or who may have imbedded metal fragments from military activities, * Patients with permanent (tattoo) eye-liner or with facial make-up (severe eye irritation has been reported), * Patients with compromised thermoregulatory systems (e.g. certain cancer patients), * Patients with metallic implants, because they may cause artifacts in diagnostic images due to magnetic field distortion, * Patients with implanted prosthetic heart valves, * Patients with pacemakers, neuro-stimulation devices, * Pregnant patients (the safety of magnetic resonance examination has not been completely established for embryos and fetuses), * Subjects who have received orthodontic work involving ferromagnetic materials, * Subjects who have claustrophobia, and * The patients unwilling to participate in the study or fail to sign the consent form. * Subjects who are pregnant or breast-feeding will be excluded from the contrast enhanced MRI studies. * Subjects who had allergic response to contrast agents previously will be excluded from contrast enhanced MRI studies. * Subjects with known history of asthma, allergic conditions, severe renal insufficiency, sickle cell anemia, chronic hemolytic anemia, gastrointestinal disorders will also be excluded from contrast enhanced MRI studies.