Effect of Recombinant FVIII in Healthy Male Subjects Treated With TB-402

Inclusion Criteria include: * Males 18 to 45 years of age * Healthy according to medical history, physical exam, ECG, blood pressure and heart rate, and laboratory profile of blood and urine Exclusion Criteria include: * Self or family history of cardiovascular or pulmonary disorder, or coagulation or bleeding disorders or reasonable suspicion of vascular malformations e.g. cerebral haemorrhage, aneurysm or premature stroke * History of important bleeding episodes * Previous allergic reaction to immunoglobulin * Present or previous history of severe allergy, for example asthma or anaphylactic reactions * FVIII:C \<50% or \>150% at screening * Clinically significant out of range values for any coagulation test during screening * Received prescribed medication, over the counter medication or herbal medicines within 14 days of receipt of TB-402