Special Survey on Parkinson's Disease (PD) Patients Without Concomitant Use of L-Dopa

Clinical Global Impression of Improvement

Investigators evaluation of the PD symptoms on a rating scale of 5 categories (very much improved, much improved, minimally improved, no effect, and unassessable).

Time frame: after 36 months treatment

Change From Baseline in Unified Parkinson's Disease Rating Scale (UPDRS) Part III Total Score

Motor examination is assessed by 27 questionnaire items in UPDRS Part III section. Each item is scored from 0 (best) to 4 (worst), and the total score of UPDRS Part III is from 0 (best) to 108 (worst). A decrease in the score means improvement.

Time frame: Baseline and at 36 months (or at the time of discontinuation)

Change From Baseline in Modified Hoehn & Yahr Rating Scale

A severity of PD symptom are assessed by Modified Hoehn \& Yahr rating scale. This scale consist of 10 levels including additional evaluation levels defined in Japan. Ten levels are described by 0 (best), 1, 1.5, 2, 2.5, 3, 3.5, 4, 4.5, 5 (worst).

Time frame: Baseline and at 36 months (or at the time of discontinuation)