Antioxidant Supplementation in Trauma Patients

Phase 3TerminatedNCT00613392

Boston Medical Center18 enrolled

Overview

Administration of antioxidants to trauma patients will improve measures of oxidant stress in the blood

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

QUADRUPLE

Enrollment

Conditions

Multiple Trauma

Interventions

powdered antioxidantDIETARY_SUPPLEMENT

one vial mixed with water every day orally or through enteral tube

powdered cornstarch placeboDIETARY_SUPPLEMENT

one vial mix with water and administer orally or via enteral tube

Eligibility

Sex: ALLMin age: 18 YearsMax age: 85 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Adult non pregnant non lactating trauma patient Exclusion Criteria: * GCS \<6 * Renal dysfunction (cre \> 2.5 mg/dl) * Hepatic dysfunction ( TBili \> 3.0 mg/dl) * Expected survival \< 48 hours * Burns over \> 20% body surface area * Immune-deficiency syndromes * Steroid use

Outcomes

Primary Outcomes

measures of malondialdehyde level/total antioxidant status and F2 isoprostane

Time frame: 7 days

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.