Novel Topical Treatment of Hand Dermatitis (Eczema)

Inclusion Criteria: Subjects must meet the following inclusion criteria: 1. 18 years of age or older; 2. have mild to moderate hand dermatitis, according to Investigator Global Assessment (see below); 3. be generally healthy, as determined by brief medical history; 4. have a negative urine test for pregnancy if female, and use of highly effective method of birth control, such as condoms \& spermacide, implants, injectables, combined oral contraceptives, intrauterine device (IUD's), sexual abstinence, or a vasectomized partner. For subjects using a hormonal contraceptive method, \[i.e., birth control pill (BCP)\], the dose and type of BCP should stay constant 1 month prior to enrollment and throughout the study, and 5. be capable of understanding and signing the consent form. Exclusion Criteria: Subjects will be excluded from the study if they: 1. have clinically relevant allergic or irritant contact dermatitis and the inability to avoid exposure; 2. have severe and very severe hand dermatitis according to the Investigator Global Assessment; 3. have severe vesiculation or bullae; 4. have a history of psoriasis, contact urticaria, and/or pustular diseases of the hands; 5. have had therapy of the hands with potent topical corticosteroids within one month of enrollment; 6. have used systemic treatment with oral retinoids, corticosteroids, or with PUVA within the 8 week period prior to the beginning of the study 7. have a history of alcoholism or drug abuse; 8. have a history or current evidence of a chronic or infectious skin disease; and 9. are pregnant or lactating females, or using method of birth control that does not comply with highly effective methods of birth control listed under inclusion criteria; Pregnant or lactating females, or using method of birth control that does not comply with highly effective methods of birth control listed under inclusion criteria.