This is a proof-of-concept study to determine if PH-797804 reduces neuropathic pain associated with post-herpetic neuralgia. Suitable patients will be randomized to receive either PH-797804 or placebo for 4 weeks, during which time they will also record their pain symptoms using various pain scales.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
80
Pfizer Investigational Site
Viña del Mar, Región de Valparaíso, Chile
Change from baseline to endpoint in weekly average pain score using the 11-point daily pain rating scale
Time frame: 4 weeks
PH-797804 pharmacokinetics
Time frame: Weeks 1, 2, and 4
Patient global impression of change
Time frame: Week 4
Neuropathic Pain Symptom Inventory
Time frame: Baseline and Weeks 1, 2, and 4
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