Lurasidone HCl is a compound developed for the treatment of schizophrenia. This clinical study is designed to test the hypothesis that lurasidone is more efficacious than placebo. The study will also evaluate the safety and tolerability of lurasidone as compared to placebo.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
478
Change in Total PANSS (Positive and Negative Syndrome Scale)Score From Baseline to the End of the Double Blind Treatment Period.
The PANSS is a 30-item rating instrument evaluating the presence/absence and severity of positive, negative and general psychopathology of schizophrenia. The scale was developed from the BPRS and the Psychopathology Rating Scale. All 30 items are rated on a 7-point scale (1=absent; 7=extreme). The total score can range from 30 to 210. Lower scores represent less severity of illness.
Time frame: Baseline and 6 weeks
CGI-S (Clinical Global Impression - Severity) Change From Baseline to the End of the Double-blind Treatment.
The CGI-S is a clinician-rated assessment of the subject's current illness state on a 7-point scale, where a higher score is associated with greater illness severity.
Time frame: 6 weeks
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Lurasidone 40 mg tablets
K&S Professional Research Services LLC
Little Rock, Arkansas, United States
Woodland International Research Group, LLC
Little Rock, Arkansas, United States
Clinical Pharmacological Studies, Inc.
Cerritos, California, United States
Excell Research
Oceanside, California, United States
University of California at Irvine Medical Center
Orange, California, United States
California Clinical Trials
Paramount, California, United States
CNRI - San Diego, LLC
San Diego, California, United States
UCSD Medical Center
San Diego, California, United States
Collaborative Neuroscience Network Inc.
Torrance, California, United States
Florida Clinical Research Center, LLC
Fruitland Park, Florida, United States
...and 42 more locations