Analysis of Microalbuminuria and Markers of Inflammation and Oxidative Stress in Adolescents of Different Ethnic Backgrounds

University of California, Davis68 enrolled

Overview

The purpose of this study is to determine if there are signs of inflammation in one's blood and urine and to find out if one's body size or ethnicity has an effect on these substances.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Inflammation

Eligibility

Sex: ALLMin age: 12 YearsMax age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Adolescents between 12 to 18 years old * Hispanic, African American or Caucasian ethnicity * Have a Body Mass Index (BMI) between the 5th and 85th percentile or greater than the 95th percentile * Must currently be attending a UC Davis Pediatric clinic Exclusion Criteria: * Chronic liver or kidney disease, known Diabetes or other chronic illnesses (such as Sickle Cell Disease or Cystic Fibrosis) * Subjects can NOT be acutely febrile, smoke, chronically use prescription medications or oral contraceptive pills.

Locations (1)

UC Davis Medical Center

Sacramento, California, United States

Outcomes

Primary Outcomes

To compare plasma levels of inflammatory markers and urinary biomarkers of oxidative stress in adolescents of Hispanic, African-American and Caucasian ethnicity

Time frame: at the end of study

Secondary Outcomes

To determine if there is an independent correlation between these markers and urinary microalbumin excretion

Time frame: at the end of study

Data from ClinicalTrials.gov

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