This study intends to compare postoperative outcomes of a tissue expander placement following a mastectomy with two different operative techniques. This study will be randomized and double blinded comparing the traditional placement of the tissue expander under an inferolateral serratus muscle flap to a new technique which uses an acellular dermal matrix as an inferolateral sling, instead of the muscle flap. The study we are proposing will evaluate the question of whether there is a difference between the traditional method of serratus flap and the new technique of using an acellular matrix with tissue expander placement. This will be a double blinded randomized study of thirty women in each group comparing outcomes which will include postoperative pain, complications (wound infection, hematoma, capsular contracture, etc), and patient satisfaction with the procedure.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
36
Dermamatrix used to cover lateral aspect of breast tissue expander after mastectomy
Traditional use of serratus anterior for coverage of lateral aspect of tissue expander
Vanderbilt University Medical Center
Nashville, Tennessee, United States
postoperative pain
Time frame: perioperative up to 1 year
aesthetic outcome
Time frame: 1 year
complications (infection, hematoma, capsular contracture)
Time frame: 1 year
Patient satisfaction
Time frame: 1 year
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