Impact of Trans Fatty Acids From Natural and Industrial Origin in the Induction of Insulin Resistance Development

Inclusion Criteria: * female * waist measurement \> 88 cm * body mass index\> 28kg/m2 * Affiliated to National Health Insurance * Subject giving his/her written informed consent * Subject willing to comply with the study procedures * Subject considered as normal after clinical examination and medical questionnaire Exclusion Criteria: * Reported food allergies * Currently participating or having participated in another clinical trial during the last 4 weeks prior to the beginning of this study * Hepatic or renal impairments * Positive serologies to HIV or HCV, determined on blood sample * pregnant or presently attempting to get pregnant or menopause or lactating Blood donation done less than 2 months before the start of the study * Chronic pathologies: diabetes, hypertriglyceridemia, hypertension, cardiovascular diseases, chronic inflammatory diseases * Intestine, cardiovascular, kidney and cancer pathologies in the last 5 years * Previous heavy intestine surgery (except appendicectomy) * Previous medical and/or surgery judged by the investigator as incompatible with this study * High variation (\> 5%) of body weight during the last 3 months * Consuming nutritional supplements which could interfered with lipid metabolism (fish oil capsule, vitamins, soja lecithins,…) * Heavy consumer of alcohol * Smoker or ex-smoker who stopped smoking less than 1 month before V0 (more than 5 cigarettes/dy). * Practising intensive physical exercise (\> 5 h per week) * Vegetarian or vegan * Being under someone's supervision * Refusal to be registered on the National Volunteers Data file * Disliking butter, margarine, cheese, biscuits and/or vegetable oil * Dietary habits unreliable to controlled food intake * Being in exclusion on the National Volunteers Data file