Pulmonary Arterial Hypertension in Systemic Sclerosis

Fondazione IRCCS Policlinico San Matteo di Pavia200 enrolled

Overview

The purpose of this study is to evaluate the role of stress echocardiography, compared to standard echocardiography in the early identification of pulmonary arterial hypertension in systemic sclerosis. To evaluate the role of BNP in this setting.To analyze data recorded with respect to the parameters commonly used for SSc evaluation (eg thorax HRCT, pulmonary function tests + DLCO, nailfold capillaroscopy, etc); these parameters are available starting for 1999.

Study Type

OBSERVATIONAL

Enrollment

200

Conditions

Systemic Sclerosis Pulmonary Arterial Hypertension

Eligibility

Sex: ALLMin age: 18 YearsMax age: 90 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients with systemic sclerosis according to LeRoy criteria Exclusion Criteria: * Pregnancy * Significant valvular disease * Low left ventricular function upon echocardiography (ejection fraction\<55%) * History of atrial fibrillation, myocardial infarction, pulmonary thromboembolisms, neoplasia or severe hepatic disease.

Locations (2)

IRCCS Foundation Policlinico S. Matteo

Pavia, PV, Italy

IRCCS Policlinico S. Matteo

Pavia, PV, Italy

Data from ClinicalTrials.gov

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