Markers of Defective Membrane Remodelling in Scott-like Syndromes

Inclusion Criteria: * Patients with unexplained provoked hemorrhages (surgery, tooth extraction, birth …), and associated with reduced prothrombin consomption (residual prothrombine in serum \> à 5%). * Family members of the patients defined above, with or without unexplained hemorrhages (symptomatic or not). * Patient's approval based on detailed information given by the pratician Exclusion Criteria: * Patients with primary hemostasis defect or defective blood coagulation factor(s) possibly explaining the bleeding disorder. * Anémia, * patients known to be affected by Factor V New York . * Patients enrolled in a previous clinical study, the exclusion period of which is not yet completed. - Collaboration to the study rejected by the patient * Patients that are not registered for medical care social insurance.