Gene Polymorphisms in Tacrolimus Drug Interactions

N/ACompletedNCT00620841

KU Leuven40 enrolled

Overview

A retrospective analysis of the influence of gene polymorphisms on drug interactions between calcineurin-inhibitors and concomitant drugs in renal transplant patients.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Renal Transplantation

Interventions

genotypingOTHER

Restriction fragment lenght polymorphisms

Eligibility

Sex: ALLMin age: 18 YearsMax age: 75 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Treatment with calcineurin-inhibitor * Renal transplantation Exclusion Criteria: * Drug, alcohol addiction

Locations (1)

University Hospitals Leuven

Leuven, Brabant, Belgium

Outcomes

Primary Outcomes

Tacrolimus exposure parameters

Time frame: weeks

Secondary Outcomes

Tacrolimus daily dosing

Time frame: weeks

Data from ClinicalTrials.gov

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