Creon in HIV Patients With Steatorrhea

Inclusion Criteria HIV positive patients with clinically stable disease (Karnofsky Performance Status \> 40); * Steatocrit \> 2 %; * Females of child-bearing potential must have a negative pregnancy test during prestudy or the subject must be surgically sterile or be at least 1 year postmenopausal as judged by the investigator; * Women of child-bearing potential must be using a medically acceptable method of birth control throughout the study Exclusion Criteria * Known allergy to pancreatin or any history of abnormal drug reaction; * Known diagnosis of pancreatic exocrine insufficiency due to e.g. chronic pancreatitis or cystic fibrosis or pancreatectomy; * Intake of an experimental drug within four weeks prior to entry into the study; * Alcohol abuse within the last six months; * Suspected non-compliance or non-cooperation; * Any other lack of fitness, in the investigator's opinion, to participate in or to complete the study; * Patients with a stool fat excretion \<= 7 g/day according to van de Kamer during the run-in period