A Trial Of [S,S]-Reboxetine In Patients With Chronic Painful Diabetic Peripheral Neuropathy.

Inclusion Criteria: * Male or female of any race at least 18 years of age * Diagnosis of painful, distal, symmetrical, sensory-motor polyneuropathy, which is due to diabetes, for at least 1 year * Patients at Visit 1 must have a score ≥40 mm on the Pain Visual Analogue Scale Exclusion Criteria: * Patients with significant hepatic impairment * Neurological disorders unrelated to diabetic neuropathy that may confuse the assessment of neuropathic pain * Any pain or other condition that may confound assessment or self-evaluation of the pain due to diabetic neuropathy * Amputations other than toes * A current or recent diagnosis (past 6 months) or episode of major depressive disorder and/or uncontrolled depression * History of transient ischemic attack or stroke * Myocardial infarction or unstable angina within the past three months