The changes in risks of developing coronary heart disease in patients with morbid obesity after different weight loss interventions have not been extensively studied. The primary objective of this study is to investigate whether an intensive lifestyle intervention program in a tertiary care clinic (Spesialsykehuset for Rehabilitering) is comparable with a 7-week low-energy-diet followed by bariatric surgery in decreasing the risk of cardiovascular disease in these patients.
Patients matching the eligibility criteria were divided into two groups (not randomized). One group underwent a 7 weeks Low-Energy-Diet before bariatric surgery, the other group participated in an intensive lifestyle intervention program for 3 months. Data on arterial stiffness, body weight, body composition, blood pressure, blood samples, vital parameters are registered in the both groups at baseline, 7 weeks and after 1 year.
Study Type
OBSERVATIONAL
Enrollment
200
Bariatric Surgery Treatment: Duodenal Switch, Gastric Sleeve or Gastric bypass.
Intensive Lifestyle Intervention Program
Morbid Obesity Center, Vestfold Hospital Trust
Tønsberg, Norway
Arterial stiffness
Pulse wave velocity and augmentation index
Time frame: 7 weeks and 1 year
Cardiovascular risk factors
Several biomarkers will be examined
Time frame: 7 weeks and 1 year
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