Labor Analgesia With Ropivacaine and Clonidine

UPECLIN HC FM Botucatu Unesp32 enrolled

Overview

The aim of the present study was to examine, for pain relief during labor, the efficacy of two pharmacological approaches - the 0.125% ropivacaine alone and the 0.0625% ropivacaine added to 75 ug clonidine, both by epidural administration. The effect of the drugs on mother and newborn was also determined.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Labor Pain

Interventions

ropivacaineDRUG

15 ml of ropivacaine 0.125% peridural once

ropivacaine and clonidineDRUG

15 ml of ropivacaine 0.0625% plus 75 mcg clonidine

Eligibility

Sex: ALLHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Singleton healthy * Full-term pregnancy * American Society of Anesthesiologists physical status I or II Exclusion Criteria: * Patients who had received opioids * History of hypersensitivity to local anesthetic or to clonidine * Fetus showed signs of possible intrauterine suffering * Fetus showed signs of possible neurological deficit

Locations (1)

College of Medicine of Botucatu

Botucatu, São Paulo, Brazil

Data from ClinicalTrials.gov

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