Biatain Ibu vs. Biatain in Painful Chronic Venous Leg Ulcers

Inclusion Criteria: * \>= 18 years of age * Chronic venous leg ulcer on the lower leg * Ulcer duration \>= 8 weeks * Pain intensity in study ulcer at least 4 on an 11-point numerical box scale (NBS): 0= no pain, 10= worst possible pain * Exudate level moderate to high * Ulcer size min 1.6 cm and max 11 cm in any direction * Ankle/brachial index \>= 0.8 * Treated with moist wound healing during the past 2 weeks prior to inclusion * Adequate compression therapy during the past 2 weeks prior to inclusion * The patient is cognitive capable of evaluating his/her pain relief and pain intensity * The patient is able to understand the treatment and is willing to comply with the treatment regimen. * The patient is able to complete the patient diary * The patient is willing and able to give written informed consent Exclusion Criteria: * Painful ulcers that have been treatment resistant to analgesics for the past 6 months or more * Pregnant or lactating women * Known and verified hypersensitivity to any content of the products used in this investigation * Local infection (bacterial imbalanced wound) in the study ulcer * Clinical infection in the study ulcer * Diseases: Vasculitis, erysipelas and cellulitis of the peri-ulcer skin * The investigator considers the patient not eligible * Diseases and conditions where ibuprofen or other analgesics are contraindicated (including known hypersensitivity to Aspirin (acetylsalicylic acid) or other analgesics, especially associated with a history of asthma, rhinitis or urticaria) * Diabetes * Use of per need medication for the past 3 days * Concomitant treatment with systemic antibiotics other than nitrofurantoin * Concomitant treatment with systemic corticosteroids (more than 10 mg/day prednisolon or equivalent) or other immunosuppressants within 1 month prior to inclusion * Concomitant treatment with cancer chemotherapeutics * Concomitant participation in other studies * Previous participation in this study