Clinical Investigation Of The Mitroflow Aortic Pericardial Heart Valve

Inclusion Criteria: * The subject is male or female 18 years old or older * The subject or subject's legal representative is willing to sign the informed consent * A bioprosthesis is the most suitable alternative for replacement of a dysfunctional or diseased native aortic valve or prosthesis accord gin to the current medical practice for valve selection at the center * The subject is able to return for all follow-up evaluations for the duration of the study (i.e. geographically stable Exclusion Criteria: * The patient has preexisting valve prosthesis in the mitral, pulmonary or tricuspid position * The patient requires a double or triple valve replacement * The patient had a Mitroflow Heart valve during the clinical study but who then had the valve explanted * The patient has active endocarditis * The subject is or will be participating in a concomitant research study of an investigational product * The subject is a minor, intravenous drug user, alcohol abuser, prisoner, institutionalized, or is unable to give informed consent * The patient has a major or progressive non-cardiac disease that, in the investigator's experience, results in a life expectancy of less than 1 year, or the implant of the device produces an unacceptable increased risk to the patient the patient is pregnant or lactating