Assessment and Determination of Chemotherapy Resistance in Newly-Diagnosed or First Relapse Leukemia Patients

Inclusion Criteria: Newly Diagnosed Subjects * The subject is male or female, aged 18 years of age or older * The subject has a diagnosis of acute lymphocytic leukemia (ALL) or acute myelogenous leukemia (AML); the subject must have a pathology-confirmed diagnosis * The subject must have a pathology-confirmed diagnosis * Acute lymphocytic leukemia (ALL) or acute myelogenous leukemia (AML) is defined as having \>25% blasts in the bone marrow and/or peripheral blood * The subject has not received any chemotherapy or treatment for their acute leukemia prior to the initial study visit * The subject is able and willing to provide written informed consent * The subject is able to understand the study and cooperate with all study instructions Relapsed Subjects * The subject is male or female, aged 18 years of age or older * The subject has a diagnosis of relapsed acute lymphocytic leukemia (ALL) or relapsed acute myelogenous leukemia (AML) * The subject must have a pathology-confirmed diagnosis * Acute lymphocytic leukemia (ALL) or acute myelogenous leukemia (AML) is defined as having ≥ 25% blasts in the bone marrow and/or peripheral blood * The subject has received one or more of the pre-identified chemotherapeutic agents for treatment of their initial acute leukemia diagnosis * The subject has not received any systemic chemotherapy or treatment for their relapsed acute leukemia * Receipt of intrathecal chemotherapy will be permissible * The subject is able and willing to provide written informed consent * The subject is able to understand the study and cooperate with all study instructions Exclusion Criteria: * The subject has an uncontrolled serious medical or psychiatric illness that, in the opinion of the investigator, would compromise the subject's safety or collection of data * The subject received treatment with an investigational drug within two weeks of the initial or subsequent study visits * Subjects under the age of 18