To compare total analgesic use at 24 hours after arthroscopic knee surgery in celecoxib-treated versus placebo-treated patients
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Enrollment
204
Pfizer Investigational Site
Phoenix, Arizona, United States
Pfizer Investigational Site
St. Petersburg, Florida, United States
Total analgesic use (hydrocodone bitartrate 5 mg/acetaminophen 500 mg [HC/APAP]) after surgery
Time frame: 24 hours
Patient Assessment of Pain, according to visual analogue scale, after surgery at rest and flexion
Time frame: 1, 2, 6, 8, 10, 12, 24, 36 hours
Time to analgesic use after surgery
Time frame: 1, 2, 6, 8, 10, 12, 24, 36 hours
Number and percentage of patients taking HC/APAP after surgery
Time frame: 1, 2, 6, 8, 10, 12, 24, 36 hours
Adverse events
Time frame: Day 7
Physical exam
Time frame: Day 7
Vital signs
Time frame: Day 7
Laboratory evaluation
Time frame: Day 7
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Pfizer Investigational Site
Baltimore, Maryland, United States
Pfizer Investigational Site
Timonium, Maryland, United States
Pfizer Investigational Site
Springfield, Massachusetts, United States
Pfizer Investigational Site
Springfield, Massachusetts, United States
Pfizer Investigational Site
Springfield, Massachusetts, United States
Pfizer Investigational Site
Springfield, Massachusetts, United States
Pfizer Investigational Site
Springfield, Missouri, United States
Pfizer Investigational Site
Columbia, South Carolina, United States
...and 8 more locations