Transient Elastography and Variceal Bleeding

University Hospital, Rouen29 enrolled

Overview

Transient elastography is a new non-invasive rapid and reproducible method, allowing evaluating liver fibrosis by measurement of liver stiffness. The aim of our study is to evaluate if the liver stiffness can predict the recurrence of upper variceal bleeding in cirrhotic patients hospitalized for variceal rupture.

Study Type

INTERVENTIONAL

Allocation

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

Conditions

Bleeding

Interventions

FibroscanDEVICE

transient elastography measure - Liver stiffness

Eligibility

Sex: ALLMin age: 18 YearsMax age: 75 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Informed consent form signed * Social security affiliation * Variceal bleeding with hematemesis or melena within 24 hours of inclusion * Age \> 18 years * Scheduled to undergo endoscopy within 24 hours of hospital admission Exclusion Criteria: * Hepatocarcinoma * Upper Gastro Intestinal bleeding for other causes than variceal bleeding * Concomitant disease with a life expectancy of less than 45 days * Rebleeding within 24 hours after first endoscopy * Technical failure of transient elastography

Locations (4)

UH Amiens

Amiens, France

UH Caen

Caen, France

UH Lille

Lille, France

Rouen University Hospital

Rouen, France

Outcomes

Primary Outcomes

Bleeding recurrence rate

Time frame: J45 post first hemorrage

Data from ClinicalTrials.gov

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