Sclerotherapy of Internal Spermatic Veins in Patients With Varicocele and Localized Prostate Cancer

Maaynei Hayesha Medical Center10 enrolled

Overview

Patients with varicocele in whon early prostate cancer will be found will undergo venographic embolization of both spermatic veins. The study hypothesis is that this procedure will induce a gradual regression of the prostate volume that may decrease prostate cancer cells. Close follow-up will ensure that necessary therapy will be provided if needed according to clinical criteria. Results in terms of prostate size PSA level and tumor size will be recorded.

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Prostate Cancer

Interventions

venographic occlusion of spermatic veinsPROCEDURE

Through the femoral vein a catheter is inserted into the spermatic veins in succession and the veins are occluded.

Eligibility

Sex: MALEMin age: 45 YearsMax age: 75 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Males age 45-75 * Prostate cancer * Presence of varicocele * No contraindication for venography Exclusion Criteria: * Diseases or medications which prevent interventional vascular procedures

Locations (1)

Maaynei Hayesha Medical Center

Bnei Brak, Israel

Outcomes

Primary Outcomes

Safety performance of the procedure. The change in tumor size and prostate cancer cells as evaluated by trans-rectal ultrasound and prostate biopsy

Time frame: one year

Secondary Outcomes

The change in size of the prostate as evaluated by ultrasound Change in PSA value. Reduction of above 20% in nocturia

Time frame: one year

Data from ClinicalTrials.gov

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