Barrett's Esophagus - 315 - 3 Way Cross Over

Inclusion Criteria: * A biopsy-proven diagnosis of Barrett's esophagus segment length greater than 2cm with no dysplasia or adenocarcinoma. * Clinically normal laboratory results and physical findings at screening. Exclusion Criteria: * A history of esophageal, gastric or duodenal surgery, including antireflux surgery or endoscopic antireflux procedures, except for simple closure of an ulcer. * Evidence of the following diseases or conditions: * Barrett's esophagus less than or greater than 2cm that is positive for high grade dysplasia or adenocarcinoma * Signs and symptoms of gastric outlet obstruction * Active peptic ulcer disease * severe liver disease * Pancreatitis * Malabsorption * Active inflammatory bowel disease * Severe pulmonary, cardiovascular or renal disease * Impaired renal function or abnormal urine sediment on repeated examinations * esophageal stricture or active, severe esophagitis.