Evaluating the Effect of Food on Absorption of Megace ES

Inclusion Criteria: * Body weight ranging from 60-100 kg (132-220 lbs) and body mass index ≥18 and ≤32 * Healthy Exclusion Criteria: * History of or any current medical conditions that could interfere with drug consumption, absorption, distribution, metabolism (eg. CYP450 inducers or inhibitors), or excretion of study drug * History of or any current medical conditions that could affect subject safety * History of frequent nausea or emesis, regardless of etiology * Participation in a clinical drug study during the 30 days preceding the initial dose * Significant illness during the 4 weeks preceding study entry * Use of any medication, including vitamins/herbal/mineral supplements, during the 7 days preceding the initial dose * Refusal or inability to abstain from food 10 hours proceeding and 4 hours following study drug administration, to consume the FDA high fat meal as directed, and to abstain from caffeine- or xanthine-containing beverages entirely during each confinement * Any history of or current drug or alcohol abuse * Prior alcohol intake exceeding the equivalent of 14 units/week (12 oz beer = 4 oz wine = 1.5 oz shot = 1 unit) on average, or consumption of any alcoholic beverages within 48 hours of study drug administration * History of smoking\>25 cigarettes/day within 45 days of study drug administration * Blood or blood products donated within 30 days prior to study drug administration, or anytime during the study, except as required by this protocol * Positive results of urine drug screen, blood alcohol by a Breathalyzer test, hepatitis B surface antigen, hepatitis B surface antibody (unless immunized), or anti-HCV