Insulin Sensitivity of the Brain in Pathogenesis of Diabetes Mellitus Type 2

University Hospital Tuebingen42 enrolled

Overview

The purpose of the study is to investigate whether insulin sensitivity of the human brain correlates with insulin sensitivity of the liver.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

SINGLE

Enrollment

Conditions

Human Physiology of Energy Homeostasis

Interventions

Human insulinDRUG

SalineDRUG

Eligibility

Sex: ALLMin age: 18 YearsMax age: 70 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Age 18-70 Risk factor(s) for type 2 diabetes (e.g. overweight, family history of diabetes) Exclusion Criteria: * Type 2 diabetes pregnancy acute or chronic diseases

Locations (2)

University Hospital Tuebingen, Internal Medicine IV

Tübingen, Germany

RECRUITING

University Hospital Tuebingen

Tübingen, Germany

RECRUITING

Outcomes

Primary Outcomes

Insulin effect on cortical function (spectral analysis)

Time frame: 2 weeks

Central Contacts

Andreas Fritsche, MD

CONTACT

+49 7071 29 80590 andreas.fritsche@med.uni-tuebingen.de

Data from ClinicalTrials.gov

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