To evaluate the steady-state systemic plasma concentrations of latanoprost acid following administration of latanoprost 0.005% (1.5 ug) in pediatric and adult subjects with glaucoma or ocular hypertension.
Pharmacokinetics and Safety
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
OTHER
Masking
NONE
Enrollment
47
latanoprost 0.005% (1.5 ug) will be administered. A single drop of latanoprost 0.005% will be instilled into both eyes by the investigator.
Pfizer Investigational Site
Artesia, California, United States
Pfizer Investigational Site
Atlanta, Georgia, United States
Pfizer Investigational Site
Atlanta, Georgia, United States
Plasma latanoprost acid concentrations at steady-state.
Time frame: 2 weeks
Adverse events related to systemic exposure of latanoprost
Time frame: 1 Day
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Pfizer Investigational Site
North Dartmouth, Massachusetts, United States
Pfizer Investigational Site
Minneapolis, Minnesota, United States
Pfizer Investigational Site
Durham, North Carolina, United States
Pfizer Investigational Site
Koebenhavn OE, Denmark
Pfizer Investigational Site
Catania, Italy
Pfizer Investigational Site
Coimbra, Portugal
Pfizer Investigational Site
Lisbon, Portugal
...and 3 more locations