Does Low-Dose Aspirin Improve Outcome in In Vitro Fertilisation/Intra Cytoplasmatic Sperm Injection (IVF/ICSI)?

Phase 3CompletedNCT00644085

University Hospital, Ghent201 enrolled

Overview

To investigate the effect of daily administration of low-dose aspirin, compared to placebo, on IVF and ICSI outcome.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

201

Conditions

Infertility

Interventions

aspirinDRUG

oral administration of aspirin 100 mg

placeboDRUG

oral administration of placebo

Eligibility

Sex: FEMALE

Medical Language ↔ Plain English

Inclusion Criteria: * Dutch-speaking women * Starting a first or second IVF/ICSI cycle Exclusion Criteria: * Women suffering from * platelet dysfunction * thrombopenia * gastro-intestinal ulcers * recurrent gastritis * aspirin hypersensitivity * Women on treatment with anticoagulants or aspirin

Locations (1)

University Hospital Ghent

Ghent, Belgium

Outcomes

Primary Outcomes

Number of oocytes retrieved

Clinical pregnancy rate per embryo transfer

Secondary Outcomes

Live birth rate per cycle

Data from ClinicalTrials.gov

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